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Resources  /  Knowledge Base  /  Food Nutrition  /  Current Article

Difference Between Water-Soluble Vitamins and Fat-Soluble Vitamins

FOOD NUTRITION: VITAMINS

Diagram

Vitamins that dissolve in water, and vitamins that dissolve in fat

Water-soluble vitamins

Vitamin C and the B vitamins. They dissolve in water, are not stored, and must be eaten often.

↓

Fat-soluble vitamins

Vitamins A, D, E and K. They dissolve in fat, are stored in fat and liver, and need fat to be absorbed.

Figure 1: Water-soluble vitamins dissolve in water and are not stored, while fat-soluble vitamins dissolve in fat and are stored in the body. Drawn in our own style from the vitamin chapters in Gropper et al., Advanced Nutrition and Human Metabolism, and in Kohlmeier, Nutrient Metabolism.

Introduction

Water-soluble vitamins and fat-soluble vitamins are both vitamins, which means both are organic compounds the body needs in small amounts, but they dissolve in different things and the body handles them differently. Water-soluble vitamins, vitamin C and the B vitamins, dissolve in water, travel in the blood, are not stored in the body, and are lost in the urine when more is eaten than needed. Fat-soluble vitamins, vitamins A, D, E and K, dissolve in fat, travel with fat, are stored in body fat and in the liver, and need fat in the meal to be absorbed.

Quick comparison

Table 1: Water-Soluble Vitamins compared with Fat-Soluble Vitamins

AspectWater-Soluble VitaminsFat-Soluble Vitamins
Which vitaminsVitamin C and the B vitamins: B1, B2, B3, B5, B6, B7, B9, B12Vitamins A, D, E and K
Dissolves inWaterFat
Stored in the bodyNo, or only in small amounts for short timesYes, in body fat and in the liver
Needed in the dietOften, because stores run out quicklyLess often, because stores last longer
Absorbed withAbsorbed directly from the gut into the bloodAbsorbed with dietary fat, carried in chylomicrons
Lost in cookingLost in cooking water and by heat, because they dissolve in waterMore stable in cooking, but lost with the fat that is thrown away
Excess eatenPassed out in the urineStored, so a large excess can build up
DeficiencyAppears quickly when the diet lacks themAppears slowly, because stores are used first
Main rolesCoenzymes in energy release and cell work, and vitamin C in collagen and defenceVision, bone health, protection of membranes, and blood clotting
Food sourcesFruits, vegetables, whole grains, meat and milkOils, liver, eggs, dairy fat and leafy greens

Scientific explanation

Definition

Water-soluble vitamins are vitamins that dissolve in water, namely vitamin C and the B vitamins, and they are not stored in the body in large amounts. Fat-soluble vitamins are vitamins that dissolve in fat, namely vitamins A, D, E and K, and they are stored in body fat and in the liver.

Working principle

Water-soluble vitamins dissolve in the water of food and of the gut, and they pass into the blood directly. Most of them act as coenzymes, helpers that enzymes need to release energy from food and to build cells, and vitamin C is needed to make collagen. Because they are not stored, the body needs a regular supply, and any excess is passed out in the urine. Fat-soluble vitamins dissolve in dietary fat, and they are absorbed with the fat into chylomicrons, the fat carriers of the gut, then stored in the liver and in body fat. Vitamin A is needed for vision, vitamin D for bone health, vitamin E protects membranes from oxidation, and vitamin K is needed for blood clotting.

Apparatus

The books used here name no laboratory apparatus for measuring or comparing either term, so no apparatus list is given.

Measurement procedure

The books used here give no standard laboratory procedure with volumes and steps for either term, so no procedure is invented here.

Factors affecting readings

For water-soluble vitamins, cooking in water and long cooking destroy or wash them out, and the freshness of the food decides how much remains. For fat-soluble vitamins, the fat in the meal decides absorption: a fat-free meal absorbs them poorly. Disease of the gut that stops fat absorption causes fat-soluble vitamin deficiency first. The books used here give no intake numbers, so none are stated.

Formulas and calculations

The books used here give no formula for either term, so no formula is given here.

Industrial applications

  • Water-soluble vitamins: fruits and vegetables, eaten fresh and cooked briefly so vitamin C and B vitamins survive.
  • Water-soluble vitamins: whole grains and meat, as sources of B vitamins.
  • Fat-soluble vitamins: vegetable oils and dairy fat, as sources of vitamins A, D and E.
  • Fat-soluble vitamins: liver and eggs, as sources of vitamins A and D.
  • Fat-soluble vitamins: leafy greens, as sources of vitamin K.
  • Both kinds: fortified foods, where vitamins are added to milk, flour and spreads.

Advantages and limitations

  • Water-soluble vitamins, advantage: excess is passed out in the urine, so a large dose is less likely to build up.
  • Water-soluble vitamins, limitation: they are not stored, so they must be eaten often, and they are lost in cooking water.
  • Fat-soluble vitamins, advantage: they are stored, so the body can draw on them between meals.
  • Fat-soluble vitamins, limitation: a large excess is stored too, so it can build up, and they need fat in the meal to be absorbed.

FAQ

What is the difference between water-soluble and fat-soluble vitamins?

Water-soluble vitamins dissolve in water, are not stored and must be eaten often, while fat-soluble vitamins dissolve in fat, are stored in fat and liver, and need fat to be absorbed.

Which vitamins are water-soluble?

Vitamin C and the B vitamins: B1, B2, B3, B5, B6, B7, B9 and B12.

Which vitamins are fat-soluble?

Vitamins A, D, E and K.

Why do water-soluble vitamins need to be eaten often?

Because the body does not store them, and the excess is passed out in the urine.

Does cooking destroy vitamins?

Water-soluble vitamins are lost in cooking water and by heat, while fat-soluble vitamins are more stable but are lost with fat that is thrown away.

References and further reading