A chronic condition, also spelled lipoedema, in which abnormal deposits of subcutaneous fat accumulate symmetrically in the legs and sometimes the arms, predominantly affecting women. Unlike ordinary obesity, lipidema fat is painful, bruises easily, and resists diet and exercise, often leading to misdiagnosis and distress. It tends to appear or worsen at hormonal milestones such as puberty, pregnancy, or menopause, suggesting a hormonal component. Management focuses on symptom relief through compression therapy, manual lymphatic drainage, and careful skin care, with liposuction used in selected cases. Recognition of lipidema as a distinct disorder has grown, improving diagnosis and support for those affected.