Enzymopathy is a disruption in enzyme function — any disease or disorder rooted in enzymes that do not work as they should. The term covers the inherited enzyme defects, where a mutated gene produces a faulty catalyst, and the acquired disruptions, where toxins, drugs, or deficiencies impair enzyme activity: lead poisoning cripples haem-synthesis enzymes, organophosphate pesticides block acetylcholinesterase, and B-vitamin deficiency starves the enzymes that need them as cofactors. The consequences follow the blocked pathway — toxic buildup upstream, product shortage downstream. Diagnosis hunts the failing step through metabolite patterns and direct activity assays; treatment replaces the product, restricts the substrate, or supplies the missing cofactor. Enzymopathy is the general name for what goes wrong when the catalysts of life misfire.