Detoxication — also spelled detoxification — is the process in which toxic compounds in the body are metabolised into ones that are less harmful and more easily excreted. It runs mainly in the liver, in two phases: first, cytochrome P450 enzymes oxidise, reduce, or hydrolyse the toxin; then conjugation enzymes attach it to molecules like glucuronic acid, sulfate, or glutathione, making it water-soluble enough for the kidneys or bile to clear. The system handles alcohol, drugs, pesticide residues, and the body’s own waste products like ammonia and bilirubin. Nutrition supports it indirectly — adequate protein supplies the amino acids for conjugation, and B vitamins drive the enzymes — but the popular idea of “detox” diets cleansing the body has no scientific basis. The liver detoxicates constantly, without help from juices or fasts.