Very low density lipoprotein, abbreviated VDLD, is a particle made by the liver to carry triglycerides and cholesterol through the bloodstream to the tissues. It is the precursor in the chain that leads to low density lipoprotein (LDL): as tissues strip triglycerides from the particle for energy, it shrinks and densifies into LDL, the cholesterol carrier most linked to arterial disease. High levels of these triglyceride-rich particles are associated with metabolic syndrome, diabetes, and cardiovascular risk. Diet influences them strongly — excess calories, sugar, alcohol, and refined carbohydrate raise them, while weight loss, exercise, and omega-3 fats lower them. They are measured in standard lipid panels.