Natamycin

Natamycin, also known as pimaricin, is a polyene macrolide antibiotic with potent antifungal activity produced by Streptomyces natalensis. In veterinary medicine it is used topically on skin and mucous membranes for treatment of ringworm in cattle and horses, with negligible absorption through dermal tissues of treated animals. It is also applied as a fungicide on bulbs such as onions and garlic. In the food industry it is far better known as preservative E235, sprayed or dipped onto the surfaces of cheeses and dry sausages to prevent mold growth without affecting flavour, since it acts only at the surface and has very low oral toxicity. Regulatory approvals specify maximum surface levels.