GRAS substances

GRAS substances are food additives which have been granted GRAS status, meaning they are Generally Recognized As Safe for their intended uses. The category covers a vast range of flavours, preservatives, enzymes and nutrients used in American food manufacturing. Manufacturers must ensure use levels match the evaluated conditions, and the FDA maintains public notices documenting each substance’s safety basis. Self-affirmed GRAS determinations are also permitted when qualified experts agree on safety, though formal notification to the FDA gives added market confidence and transparency.